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产品目录

RKIP/PEBP1抗体图片
产品货号:
Z25221
中文名称:
RKIP/PEBP1抗体
英文名称:
Anti-RKIP/PEBP1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-RKIP/PEBP1 Antibody
指标别名HCNP;HCNPpp;Neuropolypeptide h3;PBP;PEBP;PEBP 1;PEBP1;Prostatic binding protein;Raf kinase inhibitor protein;RKIP
克隆性Polyclonal
检验物种mouse,rat
应用范围WB,IHC
基因名称PEBP1
抗体来源Rabbit
抗体类型IgG
免疫原A synthetic peptide corresponding to a sequence at the N-terminus of mouse PBP(15-29aa QEVDEPPQHALRVDY),identical to the related rat sequence.
实际分子量21KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料PEBP1(Phosphatidylethanolamine-binding protein 1),also called PBP,RKIP,inhibits the phosphorylation and activation of MEK by RAF1.PEBP1 is identical to the phosphatidylethanolamine-binding protein(PBP) with a relative molecular mass of 23kD.The PEBP1 gene is mapped on 12q24.23.PEBP1 coimmunoprecipitates with RAF1 and MEK from cell lysates and colocalizes with RAF1 when examined by confocal microscopy.PEBP1 overexpression interferes with the activation of MEK and ERK,induction of AP1-dependent reporter genes,and transformation elicited by an oncogenically activated RAF1 kinase.PEBP1 expression was rapidly upregulated during induction of chemotherapy-triggered apoptosis in human prostate and breast cancer cell lines,and maximal RKIP expression correlated perfectly with the onset of apoptosis by Chatterjee et al(2004).RKIP depletion decreased the mitotic index,the number of metaphase cells,traversal times from nuclear envelope breakdown to anaphase,and an override of mitotic checkpoints induced by spindle poisons.
Uniprot IDP70296
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称phosphatidylethanolamine binding protein 1
蛋白名全称Phosphatidylethanolamine-binding protein 1(PEBP-1)
推荐稀释比
Western blot(WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:RKIP/PEBP1抗体RKIP抗体PEBP1多抗Anti-RKIP/PEBP1 Antibody
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